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Social Media

What Are the Best Meta Audiences? Top Targeting Strategies for High ROAS

Discover which Meta Ads audiences drive the strongest return on ad spend for Facebook and Instagram campaigns. Our performance media experts break down Custom Audiences, Lookalike Audiences, and native in-platform engagement signals.

When running advertising campaigns on Meta (Facebook and Instagram), your targeting configuration determines whether your budget generates profitable conversions or drains with zero return.

Between broad algorithmic delivery (Advantage+ audiences), interest-based targeting, and custom data lists, which segments consistently generate the best ROAS?

In this video session, our performance media experts share their favourite Meta Ads audiences and explain how to deploy them inside full-funnel acquisition campaigns.


Watch: Our Experts’ Favourite Meta Ads Audiences


Core Meta Audience Types Explained

1. Custom Audiences (First-Party Data)

Custom Audiences are built from users who have already interacted with your brand. Because these users have established familiarity with your products or services, Custom Audiences typically deliver the highest conversion rates and lowest CPAs in your account.

Key Custom Audience sources include:

  • Customer List Matches: Hashed email and phone number lists of past customers, high-AOV spenders, or newsletter subscribers.
  • Website Traffic via Meta Pixel & CAPI: Visitors who viewed specific product collections, added items to cart, or initiated checkout within the last 14–60 days.
  • App Activity: Users who installed your mobile app or completed in-app milestone events.

2. Lookalike Audiences (LALs)

Lookalike Audiences allow advertisers to find prospective new customers who share demographic, behavioral, and interest profiles similar to your most valuable existing buyers.

Best practices for building Lookalikes:

  • Seed Quality Matters: Build Lookalikes from your top 10–20% highest lifetime value (LTV) purchasers or repeat buyers rather than generic all-website visitors.
  • Start Narrow (1%): A 1% Lookalike represents the top 1% of users in your target country who most closely resemble your seed list. As you scale ad spend, expand into 2% and 3–5% tiers.
  • Layer Exclusions: Always exclude past purchasers and current website visitors from Lookalike prospecting ad sets to prevent overlapping ad delivery.

3. In-Platform Native Engagement Audiences

In the wake of iOS tracking restrictions and browser cookie deprecation, first-party data captured natively inside Facebook and Instagram has become indispensable:

  • Instagram & Facebook Page Engagers: Users who liked, commented, saved, or clicked on your organic posts or ads within the last 90–180 days.
  • Video Viewers: Users who watched 50%, 75%, or 95% of your Reels or video ad creatives.
  • Lead Form Openers: People who opened an on-platform Instant Form but did not complete submission.

Because these interaction signals occur entirely on Meta servers, they offer 100% data fidelity with zero attribution loss.


Audience Hygiene Checklist

Before scaling your ad sets:

  • Exclude Recent Converters: Set up exclusion rules for 30-day purchasers in top-of-funnel campaigns.
  • Consolidate Ad Sets: Avoid segmenting your budget across too many micro-audiences; give Meta’s machine learning enough conversion volume (at least 50 conversions per ad set per week) to exit the learning phase.
  • Refresh Hashed Lists: Regularly update customer lists (or connect automated CRM integrations via Zapier/Klaviyo) so your Custom and Lookalike audiences stay current.

Need help building a robust paid social strategy? Read our guide on 5 ways to guarantee Meta ads ROAS or request a free paid media audit with our advertising specialists.

Key Takeaways

  • Custom Audiences built from 1st-party customer lists bypass third-party cookie restrictions and deliver superior ROAS
  • Lookalike Audiences anchored on high-LTV purchasers identify new prospects with high buying intent
  • Native platform signals (video viewers, IG engagement, Instant Forms) mitigate iOS signal loss
  • Exclude past 30-day purchasers from prospecting ad sets to prevent budget cannibalization
  • Watch our team's video discussion for tactical audience structuring recommendations

How <imajery> Scales Profitability on Meta Ads

Navigating Meta's evolving auction dynamics and algorithm updates requires structured audience testing, first-party data activation, and conversion modeling. Our paid social specialists build scalable acquisition funnels for retail and direct-to-consumer brands.

Valerie Shoif

Valerie Shoif

Head of Paid Social

Valerie leads Paid Social at <imajery>, specializing in full-funnel Meta advertising architectures, high-converting creative testing, and multi-channel acquisition strategy.